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ISIDORe project home / Services / Cell models / Vector-borne pathogens

Vector-borne pathogens

Our cell models are available for the following types of analysis:

  • Virus quantification – infectious particles (TCID50, Plaque assay)
  • Virus quantification – non-infectious particles (qRT-PCR)
  • Neutralization
  • Cell viability/cytoxicity
  • Immunological assays (ELISA, Flow cytometry)
  • Bioimaging (Immunofluorescence, electron microscopy, confocal microscopy, histology, etc.)

To make sure that the type of analysis you are interested in can be performed in specific cell models, please do not hesitate to contact us exvivo-invivo-services@isidore-project.eu

Organoids

Human
Lung
Nose
Blood vessel
Liver
Kidney
Animal
LungCattle, Sheep, Pig
Table 1: Organoids

Air Liquid Interface (ALI) polarised cells

Human
Lung
Airway nasal
Airway tracheal
Airway bronchial
CALU-3
A549
Animal
LungCattle, Chicken, Pig
Airway nasalSheep, Pig
Airway trachealSheep, Pig, Mouse
Airway bronchialSheep, Pig
Table 2: Air Liquid Interface (ALI) polarised cells

Primary cells

Human 
Immune cells ( macrophages, dendritic cells)
Cultures from surgical specimens (Rift valley fever virus model)
Neural fetal progenitor cells
Animal
Immune cells (monocytes, macrophages, lymphocytes, dendritic cells)Cattle, Sheep, Pig
LungCattle, Sheep, Bat
Bronchial Pig
IntestineBat
Kidney Chicken
Neural progenitor cellsHorse
Table 3: Primary cells

Tissue section cultures

Human 
Lung Precision Cut slices
Animal
Lung Precision Cut slicesMouse, Hamster, Pig, Sheep, Cattle, Chicken
Liver Precision Cut slicesSheep
Table 4: Tissue section cultures

Immortalised cell lines

Human 
CALU-3 
A549
CACO-2
HEP-2
HUH-7
HEPA-RG (Rift Valley fever virus model)
Animal
VERO E6, VERO CCL81African Green Monkey
MDCKDog
LungChicken 
BronchialPig
Table 5: Immortalized cell lines

Stem cells

Human
Mesenchymal 
Animal
Mesenchymal Sheep
Table 6: Stem cells

Engineered cells

Animal
HepatocytesSheep
Maternal epithelial cellsSheep
Umbilical cord derived endothelial cellsSheep
Table 7: Engineered cells

Other

Custom cell requests may be considered.

Human 
Neuronal/Glial cells
Preparation of tissues
Swab/saliva collection devices
3D-vessel-on-a-chip
Animal
Transplacental model (maternal epithelial cells and trophoblasts)Sheep
3D-vessel-on-a-chip
Preparation of tissuesMammalian and Avian tissues
Table 9: Other cells and services